Recur1 mg

Description

Indications of Recur 1 mg

Finasteride is indicated for the treatment of male pattern hair loss (androgenic alopecia) in men only.

Theropeutic Class

Miscellaneous topical agents

Pharmacology

Finasteride, a competitive inhibitor of steroid Type II 5? reductase, an intracellular enzyme that converts the androgen testosterone into 5? dihydrotestosterone (DHT). Finasteride is a competitive and specific inhibitor of Type II 5? reductase, an intracellular enzyme that converts the androgen testosterone into DHT. Finasteride has no affinity for the androgen receptor and has no androgenic or antiandrogenic effects. Inhibition of Type II 5? reductase blocks the conversion of testosterone to DHT, resulting in significant decreases in serum and tissue DHT concentrations. In men with male pattern hair loss, the balding scalp contains miniaturised hair follicles and increased amounts of DHT compared with hairy scalp. Administration of Finasteride decreases scalp and serum DHT concentrations in these men.

Dosage & Administration of Recur 1 mg

The recommended dosage is 1 mg once a day. Recur may be administered with or without meals. In general, daily use for three months or more is necessary before benefit is observed. Continued use is recommended to sustain benefit. Withdrawal of treatment leads to reversal of effect within 12 months.

Dosage of Recur 1 mg

The recommended dosage is 1 mg once a day. Recur may be administered with or without meals. In general, daily use for three months or more is necessary before benefit is observed. Continued use is recommended to sustain benefit. Withdrawal of treatment leads to reversal of effect within 12 months.

Interaction of Recur 1 mg

No drug interactions of clinical importance have been identified.

Contraindications

Hypersensitivity to any component of this medication. Finasteride use is also contraindicated in women and paediatric patient.

Side Effects of Recur 1 mg

Finasteride is well tolerated. In clinical studies, the following adverse reactions were reported as possibly drug related in >1% of patients treated for 12 months with Finasteride 1 mg daily : decreased libido (1.8%), erectile dysfunction (1.3%), ejaculation disorder (1.2%) and decreased volume of ejaculate (0.8%).

Pregnancy & Lactation

No data found

Precautions & Warnings

Caution should be used in the administration of Recur in patients with liver function abnormalities, as Finasteride is metabolised extensively in the liver. Women who are or may potentially be pregnant should not handle crushed or broken tablets of Recur.

Drug Classes

Miscellaneous topical agents

Mode Of Action

Finasteride, a competitive inhibitor of steroid Type II 5? reductase, an intracellular enzyme that converts the androgen testosterone into 5? dihydrotestosterone (DHT). Finasteride is a competitive and specific inhibitor of Type II 5? reductase, an intracellular enzyme that converts the androgen testosterone into DHT. Finasteride has no affinity for the androgen receptor and has no androgenic or antiandrogenic effects. Inhibition of Type II 5? reductase blocks the conversion of testosterone to DHT, resulting in significant decreases in serum and tissue DHT concentrations. In men with male pattern hair loss, the balding scalp contains miniaturised hair follicles and increased amounts of DHT compared with hairy scalp. Administration of Finasteride decreases scalp and serum DHT concentrations in these men.

Pregnancy

No data found