Description
Indications
Pharmacology
Dosage
Adults with liver or kidney problems: if you have kidney problems, your doctor may give you a lower dose than stated above and increase it as needed. A reduction in dosage by half may be appropriate in patients with moderate impairment of kidney function (creatinine clearance in the range of 15-40 ml per minute). Celiprolol Hydrochloride is not recommended for patients with severely impaired kidney function (creatinine clearance less than 15 ml per minute). Use of low doses of Celiprolol Hydrochloride is recommended in patients with liver problems.
Administration
Contraindications
- are allergic to celiprolol hydrochloride or any of the ingredients of this medicine. Signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue
- have suffered an allergic reaction to a beta-blocker (propranolol, sotalol, timolol etc.) in the past
- suffer from an irregular/very slow heartbeat (known as bradycardia) or low blood pressure (hypotension)
- suffer from heart failure which is not under control (heart failure is a condition in which your heart is not pumping blood as well as it should), have an abnormal heart rhythm, difficulty breathing and swollen ankles
- suffer from missed heart beats (heart block) or other heart problems or you suffer from hardened arteries
- have severe kidney problems
- have, or have had, episodes of asthma, wheezing or other severe breathing problems
- have a rare tumour called a phaeochromocytoma that is not being treated
- have abnormal levels of acid in your blood (metabolic acidosis), usually as a result of severe illness
- are already taking theophylline (an anti-asthma medicine).
- have late stage peripheral arterial occlusive disease or Raynaud’s syndrome.
Side Effects
Common side effects (may affect up to 1 in 10 people): Dizziness or light headedness, weakness, or fainting especially when standing up from a lying position. These could be signs of low blood pressure. Skin rashes, excessive itching
Pregnancy & Lactation
Precautions & Warnings
- have liver or kidney problems
- have Prinzmetal’s angina (chest pain while resting)
- have poor blood circulation e.g. Raynaud’s, Burger’s Disease. Symptoms of Raynaud’s disease include fingers and toes changing colour when cold and tingling or painful on warming up. Your doctor will closely monitor you while taking this medicine.
- have inadequate circulation of blood through the coronary arteries.
- have ever had a skin condition known as psoriasis. Your doctor will stop this medicine if you have.
- have asthma or breathing problems due to long term lung problems (called bronchitis or emphysema)
- have a thyroid problem as the effects of an overactive thyroid gland (thyrotoxicosis) may be hidden by beta blocker medicine
- have a history of severe allergies, particularly to other medicines, including anaphylactic reactions
- need anti-allergic treatment eg. following a wasp or bee sting; your doctor may wish to interupt your Celipress treatment to prevent a possible allergic reaction.
- are diabetic. Patients with diabetes should be aware that the symptoms of low blood pressure (hypoglycaemia) may be hidden by beta blocker medicines
- have any heart failure that is under control with medication. Your doctor will give this medicine under strict medical surveillance
- have a slow or irregular heartbeat.
Use in Special Populations
Use in elderly: Your doctor may decide to lower your dose of Celipress if necessary.





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