Facid2%

Description

Indications of Facid 2%

Treatment of infections caused by susceptible organisms especially Staph eg, osteomyelitis, septicaemia, endocarditis, superinfected cystic fibrosis, pneumonia, skin & soft tissue infections, surgical & traumatic wound infections.

Theropeutic Class

Other antibiotic

Pharmacology

Fusidic acid inhibits bacterial protein synthesis by interfering with amino acid transfer from aminoacyl-tRNA to protein on the ribosomes.

Dosage & Administration of Facid 2%

Adult: 250-500 mg every 8 hourlySkin & soft tissue infection: 250 mg twice daily.

Interaction of Facid 2%

Drugs metabolized by CYP450 isoenzymes.

Contraindications

Hypersensitivity

Side Effects of Facid 2%

GI disturbances eg, dyspepsia, nausea, vomiting, epigastric pain, anorexia; jaundice & change of liver function.

Pregnancy & Lactation

No data found

Precautions & Warnings

Hepatic impairment, biliary obstruction or disease. Monitor hepatic function periodically in patients on high or prolonged oral doses. Avoid during 3rd trimester of pregnancy. Lactation. Premature, jaundiced, acidotic or seriously ill neonates.